Alzheimer’s Disease

Primary culture of cortical neurons or hippocampal neurons co-cultured with glial cells (astrocytes and microglia)
• Amyloid-β1-42 peptide injuries (induced with oligomers of peptide, for information see Callizot et al., 2013)
- Acute and chronic injuries (microglia activation)
• Glutamate and NMDA injuries
• TNF-α injuries / microglia activation