Amyotrophic Lateral Sclerosis (Lou Gehrig’s disease)

> Nerves/muscle co-culture. Human muscle fibers innervated by rat spinal cord (SC) explants
• Glutamate injury
• Amyloid-β1-42 peptide injuries

> Primary culture of motorneurons wild type and transgenic animals (SOD 1)
• Glutamate injury
• Amyloid-β1-42 peptide injuries