Parkinson’s Disease

> Primary culture of mesencephalic neurons (dopaminergic neurons)
• Mitochondrial toxins (6-OHDA, MPP+, rotenone) (Callizot et al. 2019)
• Lysosomal toxin (CBE)
• α-synuclein oligomers (neurotoxicity)

> Primary culture of mesencephalic neurons with microglial cells
• α-synuclein oligomers (neuroinflammation)