Multiple Sclerosis | Neuro-Sys

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ms.tif

PRECLINICAL MODELS | CNS | MS

Multiple Sclerosis

IN VITRO models

Co-culture of myelinating oligodendrocytes and central neurons

Induced demyelination by :

Cuprizone
LPS
IFN-γ

IN VIVO models

Currently under validation. Will be based on demyelinating effect of Cuprizone.

Other
models

#CNS
Alzheimer's
disease

#CNS
Neuronal
plasticity

#CNS
Parkinson's
disease

#CNS
Amyotrophic
Lateral
Sclerosis

#CNS
Stroke

#CNS
Huntington's
disease

#CNS
Central
Myelination

#PNS
Induced
Peripheral
Neuropathies

#PNS
Nerve
crush

#RARE DISEASES
Adreno
leukodystrophy

#RARE DISEASES
Multiple
System
Atrophy

#RARE DISEASES
Lysosomal
diseases

#BBB
BBB
penetrance

#MODE OF ACTION
CRISPR/Cas9

#MODE OF ACTION
Pharmacological
tools

#MODE OF ACTION
siRNA

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