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PRECLINICAL MODELS | CNS | NEURONAL PLASTICITY
Neuronal plasticity
IN VITRO models​
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Primary culture of hippocampal neurons:
Assessment of neuritogenisis, synaptogenesis, and branching points.
IN VIVO models
Assessment of cognitive function in aged mice.
Aged mice present with deficit in spatial memory and with lack of reactivity, compared to younger mice. We evaluate the effects of pharmacological agents on age-related cognitive impairments in senescent mice.
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