Neuronal plasticity AD CA1 area Neuron.jpg

PRECLINICAL MODELS  |  CNS  |  NEURONAL PLASTICITY

Neuronal plasticity

IN VITRO models​

Primary culture of hippocampal neurons:

Assessment of neuritogenisis, synaptogenesis, and branching points.

IN VIVO models

 

Assessment of cognitive function in aged mice.

Aged mice present with deficit in spatial memory and with lack of reactivity, compared to younger mice. We evaluate the effects of pharmacological agents on age-related cognitive impairments in senescent mice.