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PRECLINICAL MODELS | PNS | NERVE CRUSH

Nerve Crush

IN VIVO models

Sciatic nerve injury on mice to investigate peripheral nerve regeneration. Investigation of:

Functional recovery
Electromyography (EMG)
Morphometric analysis of sciatic nerve
NMJs

Other
models

#CNS
Alzheimer's
disease

#CNS
Neuronal
plasticity

#CNS
Parkinson's
disease

#CNS
Amyotrophic
Lateral
Sclerosis

#CNS
Stroke

#CNS
Huntington's
disease

#CNS
Multiple
Sclerosis

#CNS
Central
Myelination

#PNS
Induced
Peripheral
Neuropathies

#RARE DISEASES
Adreno
leukodystrophy

#RARE DISEASES
Multiple
System
Atrophy

#RARE DISEASES
Lysosomal
diseases

#BBB
BBB
penetrance

#MODE OF ACTION
CRISPR/Cas9

#MODE OF ACTION
Pharmacological
tools

#MODE OF ACTION
siRNA