Pr. Mariani, Professor of Cell Biology and Biology of aging at the University Pierre & Marie Curie (UPMC) is also practicing at the Charles Foix Hospital (Public Assistance-Paris Hospitals, AP-HP). Since its establishment in 2001, he has run the Neurobiology of Adaptive Processes Laboratory (CNRS/UPMC) which conducts research concerning the nervous system’s late stages of development, its ageing and some of its neurodegenerative pathologies.